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Clinical Trials Research
Impacting Health Through Translational Research
CCARM regularly recruits healthy and/or patient volunteers to participate in clinical research studies. For more information about the kind of research we do, or the kinds of studies that are currently recruiting, please contact the CCARM office at (204) 237-2570 or email us at ccarm@sbrc.ca
To see if you are eligible to participate in a current or future study, or to learn more about CCARM’s completed studies, see below:
Active / Currently Recruiting Studies
Effects of Canola Oil on Blood Vessel Function in Peripheral Arterial Disease (PAD)
Recruitment Status: Actively Recruiting / Seeking Participants
Study Description: Healthy volunteers for acute study: male or female, over the age of 40 years, with no chronic or acute medical conditions and no allergies to dietary oils or skim milk. Additional assessments to determine eligibility are required.
PAD participants for both the acute and chronic phases: male or female, over the age of 40 years, with a confirmed diagnosis of PAD, on a stable medication intake, and no lactose-intolerance or milk allergy.
Contact: The Study Coordinator at: 258-1206/258-1207 or email ccarm@sbrc.ca
Recruitment Status: Actively Recruiting / Seeking Participants
Study Description: Recruitment will consist of three groups of approximately 20 participants (n=60 total) who have been referred to the Vascular Surgery Clinic at St. Boniface Hospital, and who exhibit moderate hyperlipidemia. 1) Control Group : no egg consumption. 2) Classic Egg Group: consumption of 6 eggs/week as commercial classic eggs 3) Omega 3 Egg Group: consumption of 6 eggs/week as commercial Omega-3 eggs.
Contact: The Study Coordinator at: 235-3916 or email wweighell@sbgh.mb.ca
Establishing a Local Healthy Reference Population for Non-invasive Vascular Assessments
Recruitment Status: Actively Recruiting / Seeking Participants
Study Description: Research studies looking at the effects of foods on health will use several tests to measure how well a person’s blood vessels are working. Healthy people from Manitoba are needed to take these tests so we will have numbers from healthy people to compare to numbers from people who have a disease like diabetes. These tests are all done on the surface of your skin. Blood samples will also be taken.
Population Sought: Male and females between the ages of 20-80, non-smoker, with no illness/disease.
Contact: The Study Coordinator at: 258-1206/258-1207 or email ccarm@sbrc.ca
Effects of Pulse Varieties on Blood Vessel Function in Peripheral Artery Disease (PAD)
Projected Start: Actively Recruiting / Seeking Participants
Study Description: This study is designed to examine the effects of pulse varieties such as beans, peas, lentils, and chickpeas on blood vessel function in individuals with PAD. The study has three phases:
- Acute Phase: A total of 20 participants; 10 individuals with PAD and 10 healthy volunteers to test potency of the various types of pulses;
- Chronic Phase: A total of 80 participants with PAD will participate in this portion of the study for the duration of 8 weeks. Participants with PAD having completed the Acute Phase will be eligible to participate in the Chronic Phase. A total of three visits are required for screening, baseline and a final week 8 visit. Upon confirmation of eligibility and signing an informed consent form for this phase of the study, participants will be randomly assigned (n=20/group, 4 groups) to receive foods containing: whole pulses, seed coats, kernels, or pulse-free control foods.
- Follow-Up Phase: A subset of 40 participants with PAD (n=10/group, 4 groups) from the Chronic Phase will be assessed at 2, 4, and 8 weeks using similar assessments as the Chronic Phase.
Future Clinical Studies
Impact of Pulse-Enriched Foods on Cognitive Function and Cardiometabolic Health in Obese Adults
Projected Start: Fall 2012
Brief Description of Study: This study is designed to examine the effects of pulses such as beans, peas, lentils and chickpeas on blood vessel function, thinking, and memory in overweight inidivuals.
A total of 80 participants will be required to participate in a 12-week study. Visits to the study site will be required for screening, baseline, Week 6 and Week 12. Upon confirmation of eligibility and signing an informed consent form, participants will be randomly assigned (n=40/group, 2 groups) to consume 1/2 cup per day of foods containing pulses (peas, beans, lentils and chickpeas), or foods that do not contain pulses but provide the same amount of energy as the pulse foods, along with thier regular diet.
Projected Start: Spring 2012
Brief Description of Study: This study is designed to examine the effects of lentils on blood sugar, cholesterol, and blood vessel function in overweight participants.
Completed Clinical Studies
The following studies are now completed and closed to recruitment:
Study Description: A randomized, controlled study designed to explore buckwheat’s glucose lowering effects in healthy volunteers and volunteers with type 2 diabetes.
Study Description: A double-blind, randomized, controlled study designed to examine the effects of barley tortillas on blood glucose in healthy volunteers.
Study Description: The study is examining the ability of dietary flaxseed to reduce clinical symptoms of cardiovascular disease and increase exercise tolerance in patients.
Study Title: Exploring the Health Benefits Associated with Daily Pulse Consumption in Individuals with Peripheral Arterial Disease
Study Description: In this study clinical and laboratory tests were used to assess the relationship between the legume diet and changes to blood vessels and their function as they relate to onset of vascular disease. The effects of this diet on the release from fat tissue of hormones shown to prevent atherosclerosis were also examined.
Active Studies | Future Studies | Completed Studies