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Future Studies
CCARM Researchers are actively developing research protocols for clinical trials in the near future with:
- Canola – in Type 2 Diabetes
- Flaxseed – in LDL (bad) cholesterol lowering
- Pulses (beans, peas & lentils) – in obesity and cognition
- Pulses (lentils) – in obesity and cholesterol.
- Dairy/CLA – in Diabetes
- Soy – in LDL (bad) cholesterol lowering
Pending funding availability, future research may include studies using barley, bison, buckwheat, wild berries, and wheat bran.
The following proposed studies are currently in develoment:
* Please note: The below studies are currently not recruiting study volunteers at this time and are only in development. The below information is provided for informational purposes on the planned future activity of CCARM research only and is not intended as an advertisement for the recruitment of study volunteers.
Study title: Impact of Pulse-enriched Foods on Cognitive Function and Cardiometabolic Health in Obese Adults.
Principal Investigator: Dr. Carla Taylor (University of Manitoba, CCARM)
Co-investigators: Dr. Peter Zahradka (University of Manitoba, CCARM), Dr. Randy Guzman (Section of Vascular Surgery, St. Boniface General Hospital), Dr. Peter Howe (University of South Australia) and Dr. Jon Buckley (University of South Australia)
Brief Description of Study: This study is designed to examine the effects of pulses such as beans, peas, lentils, and chickpeas on blood vessel function, thinking, and memory in overweight individuals.
A total of 80 participants will be required to participate in a 12-week study. Visits to the study site will be required for screening, baseline, at Week 6 and Week 12. Upon confirmation of eligibility and signing an informed consent form, participants will be randomly assigned (n=40/group, 2 groups) to consume 1/2 cup per day of foods containing pulses (peas, beans, lentils, and chickpeas), or foods that do not contain pulses but provide the same amount of energy as the pulse foods, along thier regular diet. Before the baseline visit, participants will complete questionnaires abot thier food intake, food dislikes/dietary preferences, and memory/cognition. Participants will be given a 5-day weighed food record and a 5-day physical activity diary to complete before the baseline visit and toward the end of the 12-week study schedule. Assesments at baseline, Week 6 and at teh fina (Week 12) visits will be done to evaluate blood vessel function, memory/cognition, circulating markers in blood, and anthropometrics. A body scan to determine body fat composition will be required twice: at the beginning and end of the 12-week schedule.
Study Status: In development – Not Currently Recruiting Participants.
Projected Start: Summer 2012
Study title: Assessment of Three Instruments for the Non-invasive Measurement of Arterial Stiffness.
Principal Investigator: Dr. Peter Zahradka (University of Manitoba)
Co-investigators: Dr. Carla Taylor (University of Manitoba, CCARM); Dr. John Ducas (Univesrity of Mantioba, St. Boniface General Hospital);
Brief Description of Study: This research study will compare a new experimental non-invasive device that will measure the pulse wave against other devices that also measure pulse wave that are currently commercially available.
Study Status: In development – Not Currently Recruiting Participants.
Projected Start: Summer 2012
Proposed Study Title: A Dose Response, Randomized, Controlled, Single-Blind, Cross-Over Trial to Determine the LDL Cholesterol Lowering Effect of Ground Flaxseed in Adults with Borderline to Moderate Hypercholesterolemia
Principal Investigator: Dr. Heather Blewett (Agriculture and Agri-Food Canada, CCARM)
Brief Description of Study: This is a multi site study investigating the cholesterol lowering effect of ground flaxseed in volunteers with high LDL cholesterol. One site will be located in Winnipeg (CCARM) and another in Toronto (GI Labs Inc., yet to be confirmed). Collaborating with Dr. Blewett is the St. Boniface Hospital in Winnipeg and the Food Development Centre at Guelph.
The overall research goals are to determine the following in adult humans with borderline to moderate hypercholesterolemia:
1) Whether daily consumption of ground flax lowers cholesterol and inflammation markers in the blood;
2) The minimum effective dose of ground flax;
3) Whether daily consumption of ground flax reduces aortic blood pressure (PWA), arterial stiffness (PWA and PWV) and blood vessel damage (plasma microparticles) and improves blood vessel function (EndoPAT).
Study Status: In development – Not Currently Recruiting Participants.
Projected Start: Summer 2012