Articles Published in Refereed Journals
1) Duhamel TA and Dhalla NS. New insights into the causes of heart failure. Drug Discovery Today: Disease Mechanisms. In Press. 2008. DOI:10.1016/J.DDMEC.2007.12.001. Funded by the Canadian Institute for Health Research.
2) Duhamel TA, Xu Y, Arneja AS, and Dhalla NS. Targeting platelets for prevention and treatment of cardiovascular disease. Expert Opin Ther Targets. 11(12):1523-1533. 2007. Funded by the Canadian Institute for Health Research.
3) Duhamel TA, Green HJ, Stewart RD, Foley KP, Smith IC, and Ouyang J. Muscle metabolic, sarcoplasmic reticulum calcium cycling and blood hormonal responses to prolonged cycling with and without glucose supplementation. J. Appl. Physiol. 103(6):1986-98. 2007. Funded by the Gatorade Sports Science Institute.
4) Duhamel TA, Stewart RD, Tupling AR, Ouyang J, Green HJ. Muscle sarcoplasmic reticulum calcium regulation in humans during consecutive days of exercise and recovery. J Appl. Physiol. 103(4):1212-20. 2007. Funded by the Natural Sciences and Engineering Research Council of Canada.
5) Duhamel TA, Perco JG, and Green HJ. Manipulation of dietary carbohydrates following prolonged effort modifies muscle sarcoplasmic reticulum responses in exercising males. Am J Physiol: Regul Integr Comp Physiol. 291(4):R1100-10. 2006. Funded by the Gatorade Sports Science Institute.
6) Duhamel TA, Green HJ, Perco JG, and Ouyang J. Comparative effects of a low carbohydrate diet and exercise plus a low carbohydrate diet on muscle sarcoplasmic reticulum responses in males. Am. J. Physiol. Cell Physiol. 291(4):C607-17. 2006. Funded by NSERC and the Gatorade Sports Science Institute.
7) Duhamel TA, Perco JG, and Green HJ. Effects of prior exercise and a low carbohydrate diet on muscle sarcoplasmic reticulum function during cycling in females. J. Appl. Physiol. 101(3):695-706. 2006. Funded the Gatorade Sports Science Institute.
8) Duhamel TA, Green HJ and Ouyang J. Metabolic and sarcoplasmic reticulum Ca2+-handling cycling responses in human muscle four days after prolonged exercise. Can J Physiol Pharmacol. 83(7); 643-655. 2005. Published. Funded by NSERC and the Gatorade Sports Science Institute.
9) Duhamel TA, Green HJ, Sandiford, JD, Perco JG, Ouyang J. Effects of progressive exercise and hypoxia on human muscle sarcoplasmic reticulum function. J. Appl. Physiol. 97(1):188-96. 2004. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
10) Duhamel TA, Green HJ, Perco JG, Sandiford, JD, Ouyang J. Human muscle sarcoplasmic reticulum function during submaximal exercise in normoxia and hypoxia. J. Appl. Physiol. 97(1):180-7. 2004. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
11) Dhalla NS, Sani-Chohan HK, and Duhamel TA. Strategies for the regulation of intracellular calcium in ischemic heart disease. Future Cardiology. In press. 2008. Funded by the Canadian Institute for Health Research.
12) Green HJ, Bombardier EB, Duhamel TA, Stewart RD, Tupling AR, Ouyang J. Metabolic, Enzymatic and Transporter Responses in Human Muscle During Three Consecutive Days of Exercise and Recovery. Am J Physiol Regul Integr Comp Physiol. 2008 [Epub ahead of print] PMID: 18650322. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
13) Green HJ, Burnett ME, Duhamel TA, D'Arsigny CL, O'Donnell DE, Webb KA, Ouyang J. Abnormal Sarcoplasmic Reticulum Calcium-Sequestering Properties in Skeletal Muscle in Chronic Obstructive Pulmonary Disease. Am J Physiol Cell Physiol. In press. [Epub ahead of print]. PMID: 18508908. 2008.
14) Green HJ, Duhamel TA, Stewart RD, Tupling AR, and Ouyang J. Dissociation between changes in muscle Na+-K+-ATPase isoform abundance and activity with consecutive days of exercise and recovery. Am J Physiol: Endo Metab. 294(4):E761-7. 2008. Funded by the Natural Sciences and Engineering Research Council of Canada.
15) Green HJ, Bombardier E, Duhamel TA, Holloway GP, Moule J, Ranney DW, Tupling AR and Ouyang J. Acute responses in muscle mitochondrial and cytosolic enzyme activities during heavy intermittent exercise. J Appl Physiol. J Appl Physiol. 104(4):931-7. 2008. Funded by the Natural Sciences and Engineering Research Council of Canada.
16) Stewart RD, Duhamel TA, Tupling AR and Green HJ. Effects of consecutive days of exercise and recovery on muscle mechanical function. Med Sci Sports Exerc. 40(2):316-25. 2008. Funded by the Natural Sciences and Engineering Research Council of Canada.
17) Green HJ, Duhamel TA, Holloway GP, Moule J, Ranney DW, Tupling AR and Ouyang J. Rapid upregulation of GLUT4 and MCT4 expression during sixteen hours of heavy intermittent cycle exercise. Am J Physiol Regul, Integ Comp Physiol. 294(2):R594-600. 2008. Funded by the Natural Sciences and Engineering Research Council of Canada.
18) Dhalla NS and Duhamel TA. The paradoxes of reperfusion in the ischemic myocardium. Heart Metab 37:31-34, 2007. Funded by the Canadian Institute for Health Research.
19) Green, H.J., Duhamel, T.A., Foley, K.P., Ouyang, J., Smith, I.C. and Stewart, R.D. Glucose supplements increase human muscle in vitro Na+-K+-ATPase activity during prolonged exercise. Am. J. Physiol. Regul Integ Comp Physiol. 293(1):R354-62. 2007. Funded by the Gatorade Sports Science Institute.
20) Green, H.J., Duhamel, T.A., Holloway, G.P., Moule, J.W., Ouyang, J., Ranney, D., and Tupling, A.R. Muscle Na+-K+ -ATPase responses during 16 hours of heavy intermittent exercise. Am. J. Physiol. Endocrinol Metab. 293(2):E523-30. 2007. Funded by the Natural Sciences and Engineering Research Council of Canada.
21) Stewart, R.D., Duhamel, T.A., Foley, K.P., Ouyang, J., Smith, I.C., and Green, H.J. Protection of muscle membrane excitability during prolonged exercise with glucose supplementation. J Appl Physiol. 103(1):331-9. 2007. Funded by the Gatorade Sports Science Institute.
22) Green, H.J., Duhamel, T.A., Holloway, G.P., Moule, J., Ouyang, J., Ranney, D., and Tupling, A.R. Muscle metabolic responses during sixteen hours of heavy intermittent exercise. Can J Physiol Pharmacol. 85(6):634-645. 2007. Funded by the Natural Sciences and Engineering Research Council of Canada.
23) Tupling AR, Gramolini AO, Duhamel TA, Kondo H, Asahi M, Tsuchiya SC, Borrelli MJ, Lepock JR, Otsu K, Hori M, MacLennan DH, Green HJ. HSP70 binds to the fast-twitch skeletal muscle Sarco (endo) plasmic reticulum Ca2+-ATPase (SERCA1a) and prevents thermal inactivation. J Biol. Chem. 279(50):52382-9. 2004. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
24) Holloway GP, Green HJ, Duhamel TA, Ferth S, Moule J, Ouyang J, Tupling AR. Muscle sarcoplasmic reticulum Ca2+-cycling adaptations during 16 hours of heavy intermittent cycle exercise. J. Appl Physiol. 99(3);836-43. 2005. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
25) Sandiford, SD, Green HJ, Duhamel TA, Schertzer JD, Perco JG, and Ouyang J. Muscle Na+-K+-pump and fatigue responses to progressive exercise in normoxia and hypoxia. Am J Physiol: Regul Integr Comp Physiol. 289(2);R441-R449. 2005. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
26) Green HJ, Duhamel TA, Ferth S, Holloway GP, Thomas MM, Tupling AR, Rich SM, Yau JE. Reversal of muscle fatigue during 16 hours of heavy, intermittent cycle exercise. J. Appl. Physiol. 97(6); 2166-75. 2004. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
27) Sandiford SD, Green HJ, Duhamel TA, Perco JG, Schertzer JD, Ouyang J. Inactivation of human muscle Na+-K+-ATPase in vitro during prolonged exercise is increased with hypoxia. J. Appl. Physiol. 96: 1767-1775. 2004. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
28) Schertzer JD, Green HJ, Fowles JR, Duhamel TA, Tupling AR. Effects of prolonged exercise and recovery on sarcoplasmic reticulum Ca2+-handling properties in rat muscle homogenates. Acta Physiol Scand. 180(2): 195-208. 2004. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
29) Schertzer JD, Green HJ, Duhamel TA, Tupling AR. Mechanisms underlying increases in SR Ca2+-ATPase activity after exercise in rat skeletal muscle. Am J Physiol Endocrinol Metab. 284(3): E597-610. 2003. Published. Funded by the Natural Sciences and Engineering Research Council of Canada.
Invited Commentaries Published in Refereed Journals
30) Duhamel TA. Viewpoint: Fatigue mechanisms determining exercise performance: integrative physiology is systems physiology. J Appl Physiol. 104(5):1544. 2008.
Published Book Chapters.
31) Duhamel TA and Dhalla NS. Molecular Mechanisms of Renin-Angiotensin-Aldosterone Blockade in Congestive Heart Failure. In: Recent Advances in Cardiovascular Sciences, Ed. by S.S. Agrawal, DIPSAR, Govt. of NCT Delhi, New Delhi, In press. 2008. Funded by the Canadian Institute for Health Research.
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