St-Boniface Hospital Research


Ben Albensi

(Selected Publications)

G.L. Odero, K. Oikawa*, K.A.C. Glazner, D. Grossman, J. Thiessen, J. Schapansky, N. Ge, M. Martin, G.W. Glazner, and B.C. ALBENSI. Evidence for the Involvement of Calbindin D28k in the Presenilin 1 Model of Alzheimer’s Disease. Neuroscience 169: 532-543, 2010. *This author is a co-first author.

K.A.C. Glazner, G. Odero*, D. Grossman, E. Anema, A. Motnenko, J. Schapansky, D. Oliver, G. Glazner and B.C. ALBENSI. Strain Specific Differences in Memory and Neuropathology in a Mouse Model of Alzheimer’s Disease. Life Sciences 86: 942-950, 2010. *This author is a co-first author.

J. Thiessen, K.A.C. Glazner, S. Nafez, A. Schellenberg, R. Buist, M. Martin, and B.C. ALBENSI. Histochemical visualization and diffusion weighted imaging in the TgCRND8 transgenic model of Alzheimer’s disease. Brain Structure and Function 215(1): 29-36, 2010.

D. Zhang, R. Buist, W. Xiong, J. Peeling, B.C. ALBENSI, F.E. Parkinson. Expression of human equilibrative nucleoside transporter 1 (hENT1) in mouse neurons regulates adenosine levels in physiological and hypoxic-ischemic conditions. Journal of Neurochemistry 118(1):4-11, 2011.

S. Kost, C. Sun, W. Xiong, K. Graham, C. E Cass, J.D. Young, B.C ALBENSI, F.E Parkinson. Behavioral effects of elevated expression of human equilibrative nucleoside transporter 1 in mice. Behavioral Brain Research 224(1):44-9, 2011.

M.Z. Kastyak-Ibrahim, M.J. Nasse, M. Rak, C. Hirschmugl, M.R. Del Bigio, B.C. ALBENSI and K.M. Gough. Biochemical label-free tissue imaging with subcellular-resolution synchrotron FTIR-FPA. NeuroImage 60: 376–383, 2012.

D. Stitt, M. Z. Kastyak-Ibrahim, C. R. Liao, J. Morrison, B.C. ALBENSI, K.M. Gough. Tissue acquisition and storage associated oxidation considerations for FTIR microspectroscopic imaging of polyunsaturated fatty acids. Vibrational Spectroscopy 60:16-22, 2012.

H. Soylu, D. Zhang, R. Buist, M. Martin, B.C. ALBENSI, F.E. Parkinson. Intracortical injection of endothelin-1 induces cortical infarcts in mice: effect of neuronal expression of an adenosine transporter. Experimental & Translational Stroke Medicine 4(1):4, 2012.

K. Oikawa, G.L. Odero, E. Platt, M. Neuendorff, A. Hatherell, M.J. Bernstein, and B.C. ALBENSI. NF-B p50 Subunit Knockout Impairs Late LTP and Alters Long Term Memory in the Mouse Hippocampus. BMC Neuroscience 13:45, 2012. Noted as “Highly Accessed” by publisher on Oct 10, 2012 (989 times).

D. Zhang, S. Chu, C. Sun, W. Xiong, B.C. ALBENSI, F. E. Parkinson. Inhibition of synaptic activity in hippocampus by ATP, hypoxia or oxygen-glucose deprivation does not require CD73. PloS One 7(6):e39772, 2012.

S. Chu, Wei Xiong, D. Zhang, H. Soylu, C. Sun, B.C. ALBENSI, F.E. Parkinson. Regulation of adenosine levels during cerebral ischemia. Acta Pharmacologica Sinica. 34(1):60-6, 2013. Invited review.

C. Liao, M. Rak, J. Lund, M. Unger, E. Platt, B.C. ALBENSI, C. Hirschmugl, K. Gough. Synchrotron FTIR reveals lipid around and within amyloid plaques in transgenic mice and Alzheimer’s Disease brain. Analyst. 138(14):3991-7, 2013.

M.Z. Kastyak-Ibrahim, D.L. Di Curzio, R. Buist, S. Herrera, S. Feng, J. Kong, X.M. Li, B.C. ALBENSI, M.R. Del Bigio, M. Martin. Neurofibrillary tangles and plaques are not accompanied by white matter pathology in aged triple transgenic-Alzheimer disease mice. Magnetic Resonance Imaging. Nov;31(9):1515-21, 2014.

W.M. Snow, B.M. Stoesz, D. Kelly and B.C. ALBENSI. Roles for NF-kB and Gene Targets of NF-kB in Synaptic Plasticity, Memory, and Spatial Orientation. Molecular Neurobiology. Apr;49(2):757-7, 2014.

C. Cadonic and B.C. ALBENSI. Oscillations and NMDA receptors: their interplay create memories. Aims Neuroscience. 1(1):52-64, 2014. Invited Review.

S. Nafez, K. Oikawa, G.L. Odero, M. Sproule, N. Ge, J. Schapansky, B. Abrenica, A. Hatherell, C. Cadonic, S. Zhang, X. Song, T. Kauppinen, G.W. Glazner, M. Grilli, M.P. Czubryt, D.D. Eisenstat and B.C. ALBENSI. Early Growth Response 2 (Egr-2) Expression is Triggered by NF kB Activation. Molecular and Cellular Neuroscience. Submitted (MCN-13-103R1).

K. Oikawa, G.L. Odero, S. Nafez, N. Ging, D. Zhang, H. Kobayashi, K. Sato, S. Kimura, M. Tateno and B.C. ALBENSI. Visinin-like protein-3 modulates the interaction between cytochrome b5 and NADH-cytochrome b5-reductase in a Ca++ dependent manner. Cell Biochemistry and Biophysics. Submitted (CBBI-D-14-00066).

S.I. Omar, B.C. ALBENSI, K. Gough. Modelling the binding of Ca2+ and Zn2+ to Calbindin D28k and understanding their competition through protein structural analysis. Journal of Molecular Graphics and Modelling. Submitted.

Paul Fernyhough

*indicates papers where I am first or senior/corresponding author

Smith, D., Tweed, C., FERNYHOUGH, P. and G.W. Glazner (2009). Activation of NF-B in axons and Schwann cells at site of sciatic nerve crush and role in modulating axon regeneration: studies with etanercept. Journal of Neuropathology and Experimental Neurology. 68, 691-700. (if, 4.72)

Malisza, K.L., Jones, C., Gruwel, M.L.H., Summers, R., Smith, D.R., P. FERNYHOUGH and N.A. Calcutt (2009). Functional magnetic resonance imaging of the spinal cord during sensory stimulation in diabetic rats. Journal of Magnetic Resonance Imaging. 30, 271-276. (if, 2.21)

*Zherebitskaya, E., Akude, E., Smith, D.R. and P. FERNYHOUGH (2009). Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: role of glucose-induced oxidative stress. . Diabetes. 58, 1356-1364. (if, 8.5)

*Akude, E., Zherebitskaya, E., Roy Chowdhury, S.K., Girling, K. and P. FERNYHOUGH (2010). 4-hydroxy-2-nonenal impairs mitochondrial function and induces aberrant axonal outgrowth in adult sensory neurons that mimics features of diabetic sensory neuropathy. Neurotoxicity Research. 17, 28-38. (if, 3.0)

* FERNYHOUGH, P. and N.A. Calcutt (2010). Abnormalities in calcium homeostasis in peripheral neuropathies. Cell Calcium. 47, 130-139. (if, 4.12)

*Roy Chowdhury, S. K., Zherebitskaya, E., Smith, D.R., Akude, E., Chattopadhyay, S., Jolivalt, C.G., Calcutt, N.A. and P. FERNYHOUGH (2010). Mitochondrial respiratory chain dysfunction in lumbar dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatment. Diabetes. 59, 1082-1091. (if, 8.9)

Jackson, A.C., Kammouni, W., Zherebitskaya, E. and P. FERNYHOUGH (2010). Role of oxidative stress in rabies virus infection of adult mouse dorsal root ganglia neurons. Journal of Virology. 84, 4697-4705. (if, 5.31)

* FERNYHOUGH, P., Roy Chowdhury, S.K. and R.E. Schmidt (2010). Mitochondrial stress and the pathogenesis of diabetic neuropathy. Expert Review of Endocrinology and Metabolism. 5, 39-49.

*Roy Chowdhury, S.K., Dobrowsky, R.T. and P. FERNYHOUGH (2011). Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes. Mitochondrion. 11, 845-854. (if, 3.24)

*Saleh, A., Smith, D.R., Balakrishnan, S., Dunn, L., Martens, C., Tweed, C.W. and P. FERNYHOUGH (2011). Tumor necrosis factor a elevates neurite outgrowth through an NF-kB dependent pathway in cultured adult sensory neurons: Diminished expression in diabetes may contribute to sensory neuropathy. Brain Research. 1423, 87-95. (if, 2.62)

Jackson, A.C., Kammouni, W.and P. FERNYHOUGH (2011). Role of oxidative stress in rabies virus infection. Advances in Virus Research. 79, 127-38.

*Akude, E., Zherebitskaya, E., Roy Chowdhury, S.K., Smith, D.R., Dobrowsky, R.T. and P. FERNYHOUGH (2011). Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats. Diabetes. 60, 287-299. (if, 8.9)

Gordon Glazner

Smith D, Tweed C, Fernyhough P, Schapansky J, GLAZNER G*. (2009) Activation of NF-kappaB in Axons and Schwann cells at Site of Sciatic Nerve Crush and Role in Modulating Axon Regeneration in Adult Rats: Studies with Etanercept. Journal of Neuropathology and Experimental Neurology. 68:691-700. (*Corresponding Author)

Schapansky, J., M. Morissette, Odero, G., Albensi, B., and GLAZNER G. (2009) Neuroregulin b1 enhances peak glutamate-induced intracellular calcium levels through endoplasmmic reticulum calcium release in cultured hippocampal neurons. Can. J. Physiol. Pharmacol. 87:883-91.

Odero GL, Oikawa K, Glazner KA, Schapansky J, Grossman D, Thiessen JD, Motnenko A, Ge N, Martin M, GLAZNER GW, Albensi BC.(2010) Evidence for the involvement of calbindin D28k in the presenilin 1 model of Alzheimer’s disease. Neuroscience. 169:532-43

Glazner KA, Odero GL, Anema E, Motnenko A, Schapansky J, Grossman D, Oliver DR, GLAZNER GW, Albensi BC.(2010) Strain specific differences in memory and neuropathology in a mouse model of Alzheimer’s disease.Life Sci. 86:942-50

Hope and Healing