The Manitoba government has announced that the province will remain on Daylight Saving Time (DST) year-round, ending the seasonal change between Daylight Saving Time and Standard Time.

The change brings an end to the twice-yearly clock adjustment that has been part of life in Manitoba for decades. For two St. Boniface Hospital Research scientists, it also brings renewed attention to the science behind how we keep time and its relationship to human health.

Dr. Inna Rabinovich-Nikitin and Dr. Lorrie Kirshenbaum are University of Manitoba professors and principal investigators at St. Boniface Hospital Research. Their research has examined the relationship between circadian rhythms, cardiovascular health and the effects of changes to our biological clocks.

Their labs study the link between circadian rhythm and cardiovascular health. Their work has also examined how the circadian clock regulates important processes in the heart, including the heart’s ability to respond to stress and the survival of heart cells following a heart attack.

In 2023, St. Boniface Hospital Research highlighted their research in an article calling for an end to the seasonal time change.

While the Manitoba government has chosen to maintain Daylight Saving Time year-round, the researchers’ work highlights an important distinction between ending the clock change and choosing which time to maintain.

Standard Time better aligns social schedules with natural daylight, particularly in the morning. Permanent Daylight Saving Time, meanwhile, results in later sunrises during the winter months. The researchers emphasize that eliminating the twice-yearly disruption of changing clocks is an important step. Their concern is that maintaining Daylight Saving Time year-round may create a different type of mismatch between our social schedules and the body’s natural circadian rhythm.

“Ending the twice-yearly clock change is an important step because our biological clocks do not adjust as easily as the clocks on our walls. However, the choice of permanent time also matters. From a circadian and health perspective, Standard Time is better aligned with the natural light-dark cycle, particularly by providing earlier morning light during the winter. Permanent Daylight Saving Time would result in much later winter sunrises and greater misalignment with our biological clocks,” said Dr. Rabinovich-Nikitin.

The Canadian Society for Chronobiology has likewise called for permanent Standard Time, citing the importance of aligning the timing of daily activities with natural light and the potential health and safety effects associated with disruption to circadian rhythms.

“I’m pleased that the government has decided to eliminate the spring and fall time changes. Although standard time would align more closely with our biological clocks, maintaining one consistent time throughout the year will benefit our lifestyle, said Dr. Kirshenbaum.”

While the researchers continue to support permanent Standard Time, they welcome Manitoba’s decision to end the twice-yearly clock change and the disruption it causes to our daily lives and biological rhythms.

Related:
ICS researchers call to end Daylight Savings Time
Canadian Society for Chronobiology official statements

The St. Boniface Hospital Albrechtsen Research Centre welcomed more than 200 visitors during its recent Open House as part of Doors Open Winnipeg, offering members of the public a rare opportunity to explore research spaces, meet scientists and staff, and learn more about the work taking place within the Centre.

The event proved to be a tremendous success, with visitors arriving throughout the day to tour laboratories, participate in interactive activities, and engage directly with researchers. Attendance exceeded 200 guests, and event organizers noted that many visitors stayed for much of the day, taking the time to explore exhibits, ask questions, and learn about the discoveries and innovations happening at the Centre.

Feedback from attendees was overwhelmingly positive. Visitors expressed appreciation for the opportunity to see firsthand how research is conducted and to gain a better understanding of how scientific discoveries contribute to improving health and healthcare. Many attendees shared their fascination with the breadth of research being undertaken and expressed interest in returning for future events.

The Open House was made possible through the efforts of many individuals and teams across the Centre. Special thanks are extended to Dr. Michael Czubryt for his support of the initiative, as well as the Open House Committee for its months of planning and coordination.

The event also showcased the enthusiasm and dedication of principal investigators, research staff, students, and volunteers who welcomed visitors into laboratories and hosted displays throughout the building. The Youth BIOlab Jeunesse team provided hands-on activities that proved especially popular with guests of all ages.

Additional thanks are extended to the Parking Services and Protection Services teams for helping ensure the event ran smoothly, and to the St. Boniface Hospital Foundation for connecting with visitors and sharing the impact of research within the community. We also gratefully acknowledge Hospital Executive and President & CEO Nicole Aminot for their support of the event, as well as the team from Corporate Communications at St. Boniface Hospital for helping promote and support the Open House.

The Centre would also like to thank Doors Open Winnipeg for welcoming us as a participating site this year and for helping connect our research community with members of the public from across Winnipeg.

The success of the Open House reflects the strong interest the public has in learning about health research and the important work being conducted at the Centre. The enthusiasm, curiosity, and engagement shown by visitors throughout the day reinforced the value of opening our doors and sharing our work with the community we serve.

Planning discussions are already underway to determine what future public engagement opportunities may look like. Whether the Open House returns as an annual event, a biannual event, or in another format, organizers encourage the public to stay tuned for future announcements.

On Sunday, February 22, 2026, the Institute of Cardiovascular Sciences and St. Boniface Hospital Foundation held the third annual Mega Heart Event at The Wellness Institute in 2026.

The family-friendly heart health event is held every February to coincide with “Heart Month”. The event raises awareness on the signs and symptoms of cardiovascular health and disease prevention, with a particular focus on women’s heart health. The program featured activities such as a 2 km and 5 km family walk, Zumba sessions, CPR/AED demonstrations, interactive science exhibits, educational speaker sessions by researchers and health practitioners, kids’ activities, and giveaways. The event promotes heart-healthy lifestyles, community engagement, and disease-prevention education for all Manitobans.

At the event, Dr. Lorrie Kirshenbaum, Director of the Institute of Cardiovascular Sciences, discussed recent developments in heart research. Dr. Inna Rabinovich-Nikitin, Principal Investigator for Women’s Heart Health and Cardiometabolic Function, provided insights into heart health for women. Dr. Shuangbo Liu, an interventional cardiologist, talked about microvascular disease and shared what happens in the Cath lab. Jacqueline Hay, PhD student, at Dr. Todd Duhamel’s lab, presented on temperature & activity impacts on heart health. Their presentations highlighted the ongoing research at St. Boniface Hospital Research, focused on improving cardiovascular outcomes.

The event, attended by more than 400 participants, featured the “Science Corner” led by Steve Jones, Director of the Youth BIOlab Jeunesse, which provided visitors explore the anatomy of a pig heart, which is similar to humans and view cells through a microscope.

The event also featured important community recognition. The Honourable Uzoma Asaggwara proclaimed February 13 as Wear Red Day to support Women’s Heart Health in the Province, which was presented by MLA Jelynn Dela Cruz.  We also appreciate the presence of MLA Devi Sharma, MLA JD Devgan, and former Speaker of the Legislative Assembly Myrna Driedger for attending the event.

We thank the St. Boniface Hospital Foundation for their continued and unwavering support of this event and community research. We also thank the volunteers and sponsors who helped make the day successful,  and we value the opportunity to work with other organizations, including the HeartLife Foundation, Heart and Stroke Foundation of Canada,  Canadian Women’s Heart Health Centre, Cardiac Sciences Manitoba, Women with Medical Heart Issues, the Canadian Council of Cardiovascular Nurses, and Life in Hearts.

We remain dedicated to researching women’s heart health and supporting a program for Manitoba women facing cardiovascular issues.

Photo credit: Darin Kachanoski, The Wellness Institute

What do space travel and heart disease have in common? At the University of Manitoba and St. Boniface Hospital Research, scientists are uncovering important connections between the two.

A recent UM Today feature highlights groundbreaking work led by Drs. Lorrie Kirshenbaum and Inna Rabinovich-Nikitin, both professors at the University of Manitoba and principal investigators at St. Boniface Hospital Research. Their research examines how conditions experienced during space flight, such as microgravity and disrupted circadian rhythms, affect the heart. Supported by the Canadian Space Agency and strengthened through collaboration with NASA, their work draws on space health data to better understand cardiac stress, damage, and repair. These insights are being translated back to Earth with the potential to improve the prevention and treatment of cardiovascular disease. Read more at: https://umtoday.ca/stories/heart-health-space

To hear directly from the researchers behind discoveries like this, the University of Manitoba’s “What’s the Big Idea?” podcast offers an engaging look into their work. Hosted by UM President Michael Benarroch, the podcast features conversations with researchers whose work bridges disciplines and institutions. Episodes include discussions with Dr. Kirshenbaum on heart failure research, sex differences in cardiovascular disease, and how space-based science informs clinical research at St. Boniface Hospital. Listen to the podcast here: https://umanitoba.ca/community/whats-the-big-idea-podcast

Together, these stories show how research at St. Boniface Hospital Research and the University of Manitoba is connecting NASA, space science, and patient-focused cardiovascular research in Manitoba.

Featured image source: https://umtoday.ca/stories/heart-health-space

As we reflect on 2025, we are filled with gratitude for our incredible friends, colleagues, and supporters. Together, we celebrated meaningful achievements in research, education, and community engagement, while continuing to advance heart, metabolic, food, and population health research that improves lives in Manitoba and beyond.

This year brought moments of pride as our researchers and programs were recognized for scientific excellence, innovation, and impact. From inspiring the next generation through expanded youth outreach to advancing discovery through collaborative, world-class research, 2025 was a reminder of what is possible when curiosity, dedication, and partnership come together.

This holiday season, we celebrate the spirit of hope, discovery, and collaboration that fuels our work. Thank you for your continued support and trust, which motivates us to push boundaries and pursue excellence in everything we do.

From all of us at St. Boniface Hospital Research, we wish you and your loved ones a joyful holiday season and a New Year filled with health, happiness, and success.

We look forward to building on this momentum and continuing our journey toward better health together in 2026.

Warm regards,
The St. Boniface Hospital Research Team

Dr. Shelley Zieroth, Principal Investigator, Medical Heart Failure Program, was presented with the Canadian Heart Failure Society (CHFS) Annual Achievement Award on October 24, 2025.

This is one of the highest honours in the field. The award recognizes members who have made significant contributions to heart failure research, care, and education.

Dr. Zieroth joined the Section of Cardiology at St. Boniface Hospital in 2006 and is a Professor in the College of Medicine, Max Rady Faculty of Health Sciences, cross-appointed to the Department of Pathophysiology and Pathology at the University of Manitoba. She completed her medical, Internal Medicine, and Cardiology training at the University of Manitoba and a Postdoctoral Clinical Fellowship in Advanced Heart Failure and Cardiac Transplant at Toronto General Hospital.

Her research focuses on heart failure and cardio-kidney-metabolic interactions. She holds leadership roles in international clinical trials, serves as Associate Editor for JACC Heart Failure, the European Journal of Heart Failure, and the European Heart Journal, and is a governor for the American College of Cardiology representing Canada.

Dr. Zieroth is also Past President of the Federation of Medical Women of Canada, for which she received the King Charles III Coronation Medal in 2024, and the Canadian Heart Failure Society. She remains Co-Chair of HF Update, Canada’s largest annual heart failure meeting.

Congratulations to Dr. Zieroth on this national recognition of her leadership and impact in advancing heart failure care.

On October 15, 2025, the Youth BIOlab Jeunesse (YBL) at St. Boniface Hospital Research reached a major milestone, having worked with 100,000 students since the program began nearly two decades ago.

“On October 15, 2025, we reached an exciting milestone as 100,000 students have now participated in our outreach programs,” said Stephen Jones, Director of Youth BIOlab. “We celebrated with Grade 8 students from École communautaire Réal-Bérard in St-Pierre-Jolys, a francophone school in the Division scolaire franco-manitobaine. They dissected some hearts with Meghan Kynoch, our Program Coordinator, and joined us for some donuts afterwards. Their teacher tells us it’s the best field trip they take.”

A Brief History

• The origins of Youth BIOlab Jeunesse date back to 2005, when St. Boniface Hospital Research and the Louis Riel School Division launched an outreach program called It’s All About Me. The goal was to bring hands-on medical science experiences into classrooms.
• In 2013, the Youth BIOlab Jeunesse laboratory facility opened at the St. Boniface Hospital Albrechtsen Research Centre. This allowed for expanded programming and a dedicated space where students can engage with authentic biomedical science.
• The lab was built with support from Manitoba Education, the RBC Foundation, the St. Boniface Hospital Foundation, and other donors. National funding partners, such as the Natural Sciences and Engineering Research Council of Canada (NSERC), have also been involved.
• Youth BIOlab Jeunesse works in partnership with multiple school divisions, including but not limited to: Division scolaire franco-manitobaine, Louis Riel, Seven Oaks, Winnipeg, Seine River, Hanover, and Red River Valley.

Participation Breakdown & Reach

Of the 100,000 students who have participated:

• 48,000 have visited the lab since it opened in 2013
• 47,000 took part in school-based programs since 2005
• 5,000 joined online learning sessions

Today, the Youth BIOlab Jeunesse operates programming in 10 school divisions and collaborates with numerous other schools and community groups.

This milestone represents the continued commitment of St. Boniface Hospital, St. Boniface Hospital Research, and the Youth BIOlab to building scientific literacy and inspiring the next generation of researchers, health professionals, and innovators.

Learn more about the Youth BIOlab’s mission, partners, and programs at youthbiolab.ca

On August 25, 2025, St. Boniface Hospital Research welcomed Mark Cohen to the Albrechtsen Research Centre and the Asper Clinical Research Institute.

Decades ago, the 200-seat lecture theatre in the Research Centre was named in memory of his father, Samuel N. Cohen, a generous supporter of St. Boniface Hospital. During his visit, Mark was pleased to see his father’s name and photo displayed on the auditorium wall and to learn how significant the lecture theatre has been over the years. The space has hosted countless lectures, PhD defences, public presentations, and internationally connected conferences, making Samuel N. Cohen’s legacy a part of the research community.

Mark was welcomed by Dr. Bram Ramjiawan, Director of Research Innovation and Regulatory Affairs and Director of Research at the Asper Clinical Research Institute. He was also introduced to Dr. Michael Czubryt, Executive Director of Research at St. Boniface Hospital. Dr. Ramjiawan then led a tour beginning at the Canada Italy Tissue Engineering Laboratory (CITEL), directed by Dr. Sanjiv Dhingra, Principal Investigator. There, Dr. Dhingra and his team demonstrated how they can turn a small blood sample into stem cells and then grow them into beating heart cells. These cells help researchers study disease, test new medicines, and explore future ways to repair damaged hearts — all without any invasive procedures for patients.

The tour continued through the Asper Clinical Research Institute, where discussions focused on the importance of clinical research, how clinical trials are conducted, and the safeguards and regulations that guide them.

As a special gesture, Mark presented a meaningful gift to St. Boniface Hospital Research: an award once presented to his father in recognition of his generous support. The award, signed by past board members George Campbell MacLean and Dr. Francis Patrick Doyle, will now be proudly displayed in the Albrechtsen Research Centre.

The RBC Youth BIOlab Jeunesse (BIOlab) at St. Boniface Hospital Research has wrapped up a record-breaking and impactful 2024–2025 school year—its 20th year of full-time outreach and 11th year of operations inside its purpose-built biomedical teaching laboratory.

This year, more than 7,700 Manitoba students engaged with the BIOlab’s hands-on, curriculum-connected science programming, either on-site, in classrooms across the province, or through online sessions. Of those, over 4,500 students visited the BIOlab in person, making this the lab’s busiest year to date.

Founded in partnership with the Louis Riel School Division in 2005 and housed in the St. Boniface Hospital Albrechtsen Research Centre since 2013, the Youth BIOlab Jeunesse exists to foster health literacy, inspire scientific curiosity, and connect youth with real-world medical research. These goals are supported by a collaborative model involving multiple school divisions, generous donors, and a current 3-year PromoScience grant from the Natural Sciences and Engineering Research Council of Canada.

One of the most inspiring stories of the past year came from the ongoing collaboration with Frontier School Division (FSD). Representing Manitoba’s geographically largest division—and with over 80% of its students identifying as Indigenous—FSD partnered with the BIOlab to support students in remote communities through science mentorship, work experience placements, and virtual labs. A division-wide virtual Cardiovascular Science Day reached 340 students across 10 schools, and donations from the Manitoba Metis Federation and Manitoba Metis Heritage Fund helped bring 80 students to Winnipeg for their science fair, many of whom visited the BIOlab as a highlight of the trip.

Efforts to support Indigenous youth didn’t stop there. The BIOlab again participated in the Medical Careers Exploration Program in partnership with the Pan Am Clinic and the Winnipeg School Division, and contributed to a similar Indigenous student internship through the River East Transcona School Division.

French-language programming continued to grow under the leadership of Meghan Kynoch, who received the 2025 Prix Margaret-Teresa-McDonnell Award from Santé en français for her outstanding contributions to French health education. Meghan’s work reached over 1,500 students this year alone and highlighted the increasing demand for French-language science outreach across Manitoba.

The BIOlab also engaged with community groups such as Rossbrook House, hosting after-school science nights for inner-city youth, and supported advanced learning through inquiry-based stem cell projects with Grade 11 and 12 students from multiple divisions. Students worked with professional-grade tools like the newly acquired DeNovix CellDrop counter, giving them a taste of authentic biomedical research.

In addition to student programming, over 60 teachers participated in professional development sessions, including collaborations with the Université de Saint-Boniface and the Science Teachers Association of Manitoba. The BIOlab also continued its involvement in the Canadian Women’s Heart Health Alliance, bringing women’s cardiovascular health topics into classrooms.

Steve Jones, who has led the BIOlab’s outreach efforts since 2005, and Meghan Kynoch, who has spearheaded French programming since 2015, were instrumental in delivering another successful year. Their work, along with support from the St. Boniface Hospital Foundation, dozens of school division partners, and passionate scientists and staff, ensures that the BIOlab remains a cornerstone of youth health science education in Manitoba.

As the Youth BIOlab Jeunesse looks ahead to 2025–2026, the enthusiasm, curiosity, and imagination of Manitoba’s students continue to drive its mission forward—building a healthier, more informed future through science.

Interested in more information? The full 2025 Youth BIOlab Jeunesse Activity Report is available to download and includes detailed program data, partnership highlights, and photos from the past year’s activities.

St. Boniface Hospital Research has been awarded the 2025 Outstanding Contribution to Research Award by the Rady Faculty of Health Sciences (RFHS), University of Manitoba, a prestigious recognition presented annually to individuals or organizations that have made a significant impact on the research mission of the Rady Faculty of Health Sciences. This year, the award celebrates the collective efforts and achievements of the entire St. Boniface Hospital Research Enterprise.

This honour marks a milestone in a nearly 40-year partnership between St. Boniface Hospital and the University of Manitoba’s Rady Faculty of Health Sciences. Built on a foundation of trust, collaboration, and a shared vision, this longstanding relationship has yielded tremendous results in both research and education. Thirty Principal Investigators and clinicians based at the St. Boniface Hospital campus hold appointments through RFHS, with many also serving in leadership positions across the Faculty.

Over the decades, RFHS faculty at St. Boniface Hospital have secured tens of millions of dollars in external research funding, mentored hundreds of graduate and medical students, and contributed to numerous groundbreaking clinical trials. Thousands of peer-reviewed publications have emerged from this partnership, with frequent cross-campus collaborations. Additionally, this vibrant research ecosystem has generated over half a dozen start-up companies, originating from intellectual property developed at St. Boniface.

St. Boniface Hospital’s research programs are known for their breadth and impact. With its roots in cardiovascular research, principal investigators played a leading role in identifying diabetic cardiomyopathy, long before its existence was widely accepted. Today, the program has grown to include internationally recognized research in areas such as cardiomyocyte loss, cardio-oncology, cardiac fibrosis and regeneration, and women’s cardiovascular health, both at the lab bench and in the clinic.

The site’s strength in neuroscience has also flourished, producing meaningful contributions to Alzheimer’s disease research and paving the way for a promising first-in-human drug to reverse diabetic neuropathy, now entering clinical trials. Additional advances include new investigations into autism spectrum disorder and ALS.

Additionally, the site is exploring the health-related benefits of nutraceuticals, functional foods, and natural health products. With a focus on both discovery and public education, researchers in this area conduct basic science and clinical trials to understand how natural compounds work and their relevance to human health.

“It was truly an honour to accept this award on behalf of an incredible community of scientists, clinicians, students, and support staff – past and present – who have pushed the boundaries of research,” said Dr. Michael Czubryt, Executive Director of Research, St. Boniface Hospital. “This team has established St. Boniface Hospital Research as a powerful force for the discovery of the causes of and treatments for disease. Our impact is built on critical partnerships, including RFHS and the University of Manitoba, Agriculture and Agri-Food Canada, countless donors, and collaborators from across Canada and around the world. We are truly thankful to Dean Nickerson and the leadership of RFHS for this recognition.”

We at St. Boniface Hospital Research are excited to see the next evolution of this powerful partnership and are honoured to be recognized for the impact our team continues to make in advancing health research in Manitoba and beyond.

Featured image: Dr. Jude Uzonna [L], Vice-Dean, Research at the Rady Faculty of Health Sciences, UM, presenting to Dr. Michael Czubryt [R], Executive Director of Research, St. Boniface Hospital, accepting on behalf of St. Boniface Hospital Research. Photo credit, Scott Carnegie, Sugar Cube Entertainment

A new graduate student award has been established to honour one of Canada’s most distinguished scientists. The Dr. Grant Pierce Diabetes Research Prize is now open for applications from graduate students completing their degrees at the St. Boniface Hospital Albrechtsen Research Centre. This annual award, valued at $1,000 and accompanied by a commemorative plaque, will recognize the exceptional academic and research accomplishments of students earning either a Master’s or Ph.D. from an accredited Manitoba-based university.

Funded through a generous contribution from the Diabetes Research and Treatment Centre Winnipeg Inc. (DRTC) Endowment Fund and administered by the St. Boniface Hospital Foundation, the Prize gives preference to students whose work has focused on diabetes and related health issues. In addition to highlighting outstanding research, this new award celebrates the profound impact Dr. Grant N. Pierce has had as a scientist, educator, and leader in health research across Manitoba, Canada, and the world.

A Career of Impact

Dr. Grant Pierce has long been recognized as a towering figure in cardiovascular and metabolic research. Over a career spanning more than three decades, he has conducted groundbreaking work on heart disease, stroke, hypertension, and diabetes. His pioneering research into the therapeutic potential of nutraceuticals has changed the way clinicians and researchers approach cardiovascular prevention, demonstrating natural solutions to high blood pressure and heart disease that are now recognized internationally.

With over 250 peer-reviewed publications, an H-index of 70, and more than 15,000 citations, Dr. Pierce’s scientific influence is indisputable. But what truly sets him apart is his unwavering commitment to mentorship, collaboration, and building a legacy that extends far beyond the laboratory bench.

Building Institutions and Inspiring Generations

At the heart of Dr. Pierce’s legacy is the St. Boniface Hospital Albrechtsen Research Centre itself. As one of the founding architects of the Centre in 1987, he played a central role in its transformation from a modest grouping of six research teams into one of Canada’s most prestigious biomedical research institutions. Under his leadership as Executive Director of Research (2005–2020), the facility expanded significantly, bringing together a large and diverse group of researchers across three key programs:

• The Institute of Cardiovascular Sciences (ICS), which expanded under his leadership, became a world leader in heart failure, oxidative stress, women’s heart health, and tissue engineering.
• Division of Neurodegenerative and Neurodevelopmental Disorders (DNND), focused on aging, memory, and diseases such as dementia and stroke.
• The Canadian Centre for Agri-Food Research in Health and Medicine (CCARM), which Dr. Pierce helped establish to study the health impacts of functional foods and nutraceuticals.

Thanks to Dr. Pierce’s strategic direction, St. Boniface Hospital was recognized for twelve consecutive years as the most research-intensive small hospital in Western Canada. His efforts in recruitment, funding, and program development attracted top-tier global talent and positioned Winnipeg as a centre for medical research excellence.

A National and International Leader

His leadership role in Canadian research agencies is noteworthy, having served on the boards of Friends of CIHR and the Diabetes Research and Treatment Centre for many years.

Dr. Pierce’s influence extends well beyond provincial borders. He currently serves as World President of the International Academy of Cardiovascular Sciences, a role that underscores his global leadership in heart research. His collaborations with institutions such as the Mayo Clinic and the University of Rome have fostered innovation and brought global attention to Manitoba-based science.

His many accolades—including the Order of Canada (2023), the Order of Manitoba (2018), Fellowship in the Royal Society of Canada, and multiple awards for academic excellence—reflect the national and international recognition he has earned for his contributions.

Mentorship and Education: A Lifelong Passion

Perhaps one of Dr. Pierce’s most enduring legacies is his passion for education. He has mentored countless students, research technicians, and visiting scientists over the years, many of whom now hold leadership roles in academia and health care. The programs he championed, such as the RBC Youth BIOlab Jeunesse, have introduced generations of students to the world of biomedical research, inspiring the next generation of scientists and clinicians.

The Dr. Grant Pierce Diabetes Research Prize is a natural endorsement of this commitment. By supporting and celebrating emerging researchers, the Prize ensures that his spirit of mentorship and excellence will continue to shape future discoveries in diabetes and metabolic health.

A Tribute to Leadership, Discovery, and Dedication

In creating this award, the DRTC and the St. Boniface Hospital Foundation not only recognize Dr. Pierce’s scientific achievements but also honour the collaborative, visionary leadership that has defined his career. His legacy lives on in the institutions he built, the students he mentored, and the countless lives improved by his research.

The prize will serve to recognize the achievements of future generations of health researchers in the tradition of Dr. Grant Pierce.

For Dr. Randy Aitken, DVM, the journey of veterinary care has never been just about treating animals; it’s been about fostering relationships, nurturing trust, and creating an environment where expertise and empathy work hand in hand. After a distinguished career that has spanned decades, Dr. Aitken is preparing for the next chapter of his life, one that promises to be just as fulfilling as his time in veterinary medicine. As he reflects on his tenure in the field, it becomes clear that his legacy is defined by more than just medical skills—it’s defined by the deep bonds he’s built with colleagues, students, and the animals under his care.

A Career Built on Teamwork and Trust

Dr. Aitken’s work has always been deeply collaborative, a fact that has played a crucial role in his success. His team—comprising technical specialists, veterinary nurses, and administrative staff—has been the backbone of his career. These groups, he explains, work together seamlessly to ensure the best outcomes for both the animals and the researchers they serve.

“We’ve got a really diverse skill set within our team,” Dr. Aitken says. “The technicians, the nurses, and the administrative staff, they all play integral roles. And it’s been a privilege to work alongside these dedicated professionals. What we’ve accomplished here is really the result of all their hard work, just as much as it is mine.”

Dr. Aitken emphasizes the importance of his team in evaluating animal welfare, a responsibility that falls not just to researchers but to everyone involved in animal care. His group helps researchers determine whether a given experiment or procedure is ethically acceptable, ensuring that the animals’ well-being is always prioritized.

But it’s not just the technical and medical staff that Dr. Aitken holds in high regard. His relationships with support staff—those who work behind the scenes—have been just as impactful. “From the security guards to the housekeeping team, everyone here contributes to creating a space where people feel valued, supported, and part of something bigger than themselves,” he says. “This isn’t just a place to work—it’s a community.”

The People Who Shaped His Career

As he looks back on his journey, Dr. Aitken credits many individuals with shaping his career and creating the culture he’s so proud of. While he acknowledges his own role in crafting the team’s vision, he’s quick to point out that he couldn’t have done it alone.

“I’ve been fortunate to work with some incredible directors and colleagues throughout my career,” he shares. “People like Karen, Rob, Nicole, Nancy, Brenda and Sherry—these individuals are integral in building the foundation that made this place what it is today.”

Dr. Aitken highlights the leadership of the last three Executive Directors of Albrechtsen, Drs. Foerster, Pierce and Czubryt, each of whom brought something unique to the table. But it’s not just the leadership that stands out to him. He also speaks with fondness about the students and researchers who have passed through the facility. Many of them have returned to thank him and his team for their support and guidance, expressing gratitude for their time spent working at the facility.

“Many students come back after they’ve finished their studies and tell us how much they appreciated the environment we created here,” Dr. Aitken says. “They say it was like a second home to them. That’s what we were striving for—a place where everyone feels included, supported, and part of a shared mission.”

This sense of belonging and purpose has been a defining characteristic of the institution. Dr. Aitken attributes much of this to the culture of inclusivity that has permeated the facility. It’s more than just about getting the job done—it’s about doing it together. This feeling of shared purpose, he explains, is what has kept people coming back year after year, even after they’ve moved on to new opportunities.

“You know, you have people from all over the world coming here, people with diverse backgrounds and experiences,” he says. “And they all feel embraced and part of something bigger. That’s something I’m incredibly proud of.”

Challenges and Triumphs

Of course, any successful career comes with its challenges. For Dr. Aitken, one of the toughest aspects of his work has been navigating the difficult conversations that arise when ethical concerns need to be addressed. It’s not always easy to tell researchers that their proposed methods may not meet the required ethical standards. “Sometimes it’s tough to be the one to deliver bad news, but it’s part of our responsibility,” he says. “I’ve always approached those conversations with empathy and understanding because it’s not just about the animals—it’s about helping people make the right choices.”

Despite these tough moments, Dr. Aitken has found great fulfillment in being a part of a system that is committed to the highest standards of animal welfare. His career has been marked by a deep respect for the animals he’s cared for, and he’s equally committed to ensuring that those who work alongside him understand the importance of treating each animal with dignity and respect.

“There’s a responsibility that comes with this work,” he notes. “But there’s also a deep sense of pride. When you’re helping an animal, whether it’s in a research setting or a clinical one, you’re making a difference. And that’s something that I’ll always hold dear.”

Looking Toward the Future

As Dr. Aitken prepares to enter retirement, he reflects on the future with both excitement and a touch of uncertainty. While he’s eager to step away from the daily grind, he’s not planning to fade into the background. Instead, he’s considering a number of possibilities for the next chapter of his life.

One such possibility is exploring a role in bee health—a topic that has gained considerable attention in recent years due to the global decline in bee populations. Dr. Aitken was contacted years ago by the province’s Chief Veterinary Medical Officer to assist with research and efforts related to bee health, and he’s intrigued by the challenge.

“I’ve always been interested in the balance between animals, nature, and the environment,” Dr. Aitken says. “Bees play such an essential role in pollination and agriculture, and there’s a real need for expertise in this area. It could be a fun and fulfilling way to continue making a difference.”

But it’s not just bees that Dr. Aitken is interested in. He also enjoys the idea of returning to his roots in agriculture, particularly in working with cattle. Having spent time as a veterinary student in a feedlot, Dr. Aitken fondly recalls the experience of working with cows and feels a pull to reconnect with the world of livestock.

“I spent a week in a feedlot years ago, and I just loved it,” he says with a smile. “It was hard work, but it was rewarding. There’s something special about working with animals like that—whether it’s cattle, horses, or even just spending time on a ranch. It’s a lifestyle I’ve always admired.”

At the same time, Dr. Aitken remains deeply committed to his wife, a fellow veterinarian who recently sold her practice and is now focused on travelling and volunteering. Together, they look forward to exploring the world, though Dr. Aitken admits he’s not as drawn to the idea of globetrotting as his wife is. “She’s got the travel bug,” he laughs. “I’m more of a homebody, but I’ll go wherever she wants to go if it keeps her happy.”

As for volunteerism, Dr. Aitken has spent much of his life serving on boards and engaging with nonprofit organizations. His dedication to community service is evident in his work with professional associations and advocacy groups, as well as his role as the president of Manitoba’s largest minor hockey association.

While he’s “boarded out” for the moment, Dr. Aitken remains open to new volunteer opportunities. He envisions a future where he can contribute to a cause he believes in, perhaps in a more hands-on capacity. Whether it’s working with a nonprofit or offering his expertise to an organization in need, Dr. Aitken’s passion for service is unwavering.

A Career Well-Lived

Looking back on his career, Dr. Aitken is proud of the work he’s done and the relationships he’s built along the way. But as he prepares for retirement, he knows the impact of his work extends far beyond the walls of the clinic or the lab.

“When I think about my career, I often liken it to a gardener planting trees. Some trees represent the young colleagues I’ve recruited, mentored, and helped grow into strong professionals. Others are the processes that have improved our scientific work, and some are the cultural shifts, like fostering respect for animal welfare. Many of the trees I’ve helped plant are now mature, and I’ve been fortunate to enjoy the shade they provide. Others are still growing, and I hope they’ll continue to offer shade for future generations long after I’m gone. So, at the end of the day, I hope I’ll be remembered for the trees.”

The St. Boniface Hospital Research community acknowledges the passing of Dr. Henry Friesen on April 30, 2025, at the age of 90. This article reflects upon his extraordinary life and the lasting impact he made on science and healthcare across Canada and the globe.

Dr. Friesen’s legacy is deeply rooted in his groundbreaking research in endocrinology, a field dedicated to understanding the intricate world of hormones. His groundbreaking work led to the isolation and purification of human prolactin, offering insights into infertility and reproductive disorders and resulting in a fertility-enhancing drug, enabling many to conceive and give birth.

Beyond his remarkable scientific discoveries, Dr. Friesen played an instrumental role in the creation of the Canadian Institutes of Health Research (CIHR). From 1999 to 2000, Dr. Friesen served as the chair of the Interim Governing Council, the body responsible for recommending the establishment of CIHR.

Following his work in establishing CIHR, Dr. Friesen continued to shape Canadian research as the founding chair of Genome Canada, a role he held from 2000 to 2005. Genome Canada was established as the federal government’s lead corporation dedicated to supporting genomics research across the nation.

He played a significant role with the Manitoba Health Research Council (MHRC), responsible for assembling and chairing its first Scientific Review Committee. This early engagement at the provincial level demonstrates a long-standing commitment to nurturing and advancing health research across different scales.

Dr. Friesen’s distinguished career also encompassed a significant and impactful academic journey. In 1965, he was appointed to McGill University and the Royal Victoria Hospital. He later returned to his home province in 1973, joining the University of Manitoba, where he served as professor and head of the department of physiology and professor of medicine until 1991. His dedication to the University of Manitoba continued long after his formal tenure, as he held the esteemed title of Distinguished Professor Emeritus. Dr. Friesen authored more than 460 publications in the field of endocrinology.

Dr. Friesen received numerous accolades, including being appointed an Officer and later a Companion of the Order of Canada, induction into the Canadian Medical Hall of Fame, and being named a Distinguished Fellow of the Canadian Academy of Health Sciences. The University of Manitoba awarded him an honorary doctorate and established the Henry G. Friesen Endowed Chair in his honour.

While Dr. Friesen’s primary academic affiliations were with the University of Manitoba and McGill University, his connection to St. Boniface Hospital Research is also noteworthy.

Dr. Friesen previously served as the Chair of the Research Enterprise Committee at St. Boniface Hospital Research, indicating his active involvement in the strategic direction of research at the institution.

“We have lost a true Canadian scientific treasure,” said Dr. Grant Pierce, past Director of Research at St. Boniface Hospital. “His participation as Chair of the Research Review Committee of the Hospital Board brought credibility and sage guidance to the research directions at the Albrechtsen Research Centre. When Dr. Friesen spoke, we all listened. His voice, a strong advocate for the importance of medical and health research, will be sorely missed.”

“For 15 years, I have had the privilege of serving on a Hospital Committee with Dr. Henry Friesen, for which he was the chair,” said Dr. Bram Ramjiawan, Director of Clinical Research, Asper Clinical Research Institute. “Henry will always be respected for his incredible width of knowledge, his clarity and his leadership. His continued support towards having a better hospital, university and wider community will be remembered.”

Dr. Ian M.C. Dixon, also a Principal Investigator at the Institute of Cardiovascular Sciences, reflected on his time with Dr. Friesen:

“Everyone at St. Boniface Research Centre is saddened that our friend (and also our professor and mentor) has passed away. Dr. Henry Friesen was no ordinary man – extraordinarily kind, completely devoted to the service of others, and without the trappings of ego, despite his eminent achievements within Canadian science.  Henry developed the Department of Physiology and Pathophysiology through effective recruiting and hiring of key individuals, didactic course development and student-centric policies.  The ties he maintained within the Division of Cardiovascular Sciences and Disease were extraordinarily strong.  It can be argued that without his help, the formation of the Institute of Cardiovascular Sciences at the St. Boniface campus would not have received the go-ahead from the University Senate. Henry’s integrity, deep commitment in promoting basic and clinical research, scholarly activity, teaching and training left a lasting mark on research activity at the University of Manitoba and Canadian science.”

“His scientific stature was remarkable and enabled him to be an incredibly able role model and mentor. Henry inspired a very large number of trainees and faculty over the years (even those not directly under his supervision), and such was the magnitude of his influence. Many of his trainees have themselves become notable leaders in their fields.”

A significant and enduring connection is the “Henry Friesen Young Scientist Award,” a prestigious recognition within the Institute of Cardiovascular Sciences at St. Boniface Hospital Research. This award directly supports and encourages the next generation of researchers in cardiovascular science, embodying Dr. Friesen’s commitment to mentorship and fostering scientific talent.

Dr. Lorrie Kirshenbaum, Director of the Institute of Cardiovascular Sciences at St. Boniface Hospital, said:

“It is with profound sadness that our dear friend, mentor and visionary has passed away. He was a champion of the Department of Physiology and a strong advocate of the Division of Cardiovascular Sciences and Disease. His stalwart commitment to promoting research, scholarly activity, teaching and training left an indelible mark on research activity at the University of Manitoba, Canada and the World.  His vision was instrumental in the creation of the Institute of Cardiovascular Sciences at St. Boniface Hospital, which is acclaimed internationally. Dr. Friesen’s contributions over his long career were many, and he will be remembered as a role model, mentor and colleague to many of us over the years. Dr. Friesen was kind-hearted and inspired countless trainees and faculty over the years, who have become great leaders in their fields. The saying that “Greatness leads to greatness” in Dr. Friesen’s case was so true. I can personally say that I am privileged to have known this brilliant and special man. He was a great friend of the Institute of Cardiovascular Sciences, and he will be sadly missed.”

The strong professional relationship between Dr. Naranjan Dhalla, a key figure at St. Boniface Hospital Research and the founder of the Institute of Cardiovascular Sciences, and Dr. Friesen further underscores this connection:

 “I have known Dr. Henry Friesen, an extraordinary human being, for more than five decades and had the privilege to become one of his close friends. His conversations were most inspiring, and his advice was greatly helpful in finding solutions to diverse professional problems. He was highly committed to promoting excellence in research, not only in Manitoba but also throughout Canada. He will always be remembered with the highest respect as one of the best medical men of this country.”

Dr. Michael Czubryt, Executive Director of Research at St. Boniface Hospital, said:

“It is rare for individuals to have local, national and international impact in research, in academics, and in administration, and rarer still for one person to impact so deeply in all three areas together. Dr. Henry Friesen was that exceptionally rare individual. Just as we remember and celebrate his tremendous global impact, we also cherish the legacies he left at the local level, building up both the University of Manitoba and St. Boniface Hospital Research. We thank Henry for sharing with us his energy, his dedication, and his brilliance, and we thank his family for sharing Henry with us these many years.”

The passing of Dr. Friesen is a profound loss, and St. Boniface Hospital Research extends condolences to his family. His leadership and contributions have left an enduring legacy on Canadian and global medical research.

Today, the Youth BIOlab Jeunesse within St. Boniface Hospital Research hosted students from the Indigenous Student Work Experience Program (ISWEP). Stephen Jones, the Director, led a session on heart disease and tissue engineering, utilizing live cardiac fibroblast cells in the morning and conducting a pig heart dissection in the afternoon.

St. Boniface Hospital is in the second year of ISWEP, a 17-week internship designed to provide Indigenous youth with invaluable skills and exposure to the diverse world of healthcare. This year, the program has doubled in size, welcoming eleven Grade 11 and 12 students from the River East Transcona School Division.

The ISWEP internship offers a comprehensive experience that goes beyond typical job shadowing. Students engage in rotations through various clinical and non-clinical departments across the hospital, exploring different specialties and broadening their understanding of the healthcare sector. This hands-on experience is crucial in helping them shape their future career paths. The program is a vital step in responding to the health directives outlined in the 94 Calls to Action. A key objective of ISWEP is to increase the representation of Indigenous peoples in all positions across the St. Boniface Hospital campus.

St. Boniface Hospital Research is proud to announce that Meghan Kynoch, Program Coordinator at the Youth BIOlab Jeunesse, has been named the recipient of the prestigious 2025 Margaret-Teresa-McDonell Award for her outstanding commitment to providing high-quality health or social services in French.

As the driving force behind the Youth BIOlab’s French programming, Meghan has dedicated her career to engaging students in hands-on learning experiences that bridge the gap between classroom science and real-world health applications. She helped develop a fully immersive French-language experience to thousands of Francophone learners across the province since 2015 and her work has significantly fostered strong partnerships with Manitoba’s Division scolaire franco-manitobaine (DSFM) and French Immersion schools.

“Thanks to her leadership and expertise, approximately 25% of the 6,410 students who participated in Youth BIOlab programming during the 2023-2024 school year received instruction in French,” said Youth BIOlab Director, Stephen Jones.  “Through her dedication, she not only strengthens health literacy in the community but also inspires the next generation of bilingual health professionals.”

A French Immersion graduate herself, Meghan brings a deep understanding of language learning to her work. She has developed original, curriculum-aligned French content, providing students with real-world exposure to the biomedical sciences in ways that are both accessible and engaging. Her talent for making complex medical and scientific concepts understandable, even in a second language, is a testament to her creativity and dedication.

The Margaret-Teresa-McDonell Award, named in honour of a pioneering figure in St. Boniface healthcare history, celebrates individuals who exemplify excellence in delivering French-language health and social services. Meghan’s tireless efforts in fostering French-language health science education make her a deserving recipient of this prestigious recognition.

Congratulations, Meghan, on this well-deserved honour.

The First International Conference on Advances in the Health Benefits of Agri-Foods, held from October 2-4, 2024, brought together experts from around the world to showcase cutting-edge research in using food to achieve health benefits beyond basic nutrition. Organized and chaired by Dr. Thomas Netticadan, Team Leader of the Canadian Centre for Agri-Food Research in Health and Medicine (CCARM) and Agriculture and Agri-Food Canada (AAFC), the event marked a milestone in CCARM’s 25-year history.

The conference featured a collaborative leadership team including Dr. Cristina Rosell (Head, Food and Human Nutritional Science, University of Manitoba), Dr. Rotimi Aluko (Director, Richardson Centre for Food Technology and Research), Dr. Miyoung Suh (Professor, University of Manitoba), and CCARM trainees Dr. Ruchira Nandasiri, Dr. Nicola Gasparre, and Bradley Feltham. Julie Schoffner, CCARM administrative assistant, coordinated the event.

Distinguished speakers included Dr. Felicitas Katepa-Mpundowa (Director General, AAFC), Nicole Aminot (CEO, St. Boniface Hospital), and Dr. Tony Savard (Director, AAFC), who provided opening remarks. A plenary lecture was delivered by Dr. Grant Pierce, a founding figure of CCARM and Distinguished Professor at the University of Manitoba. Closing remarks were offered by senior leaders from AAFC, St. Boniface Hospital Research Centre, and the University of Manitoba, including Dr. Scott Duguid, Dr. Michael Czubryt, Dr. Bram Ramjiawan, Dr. Rosell, Dr. Aluko, and Dr. Suh.

The three-day hybrid conference, accessible at no cost, welcomed over 300 in-person attendees and 500 online participants from 60 countries on all continents except Antarctica. A total of 16 scientific sessions featured 80 speakers addressing diverse topics along the agri-food value chain, including:

•          Plant breeding innovations for nutritional and health benefits,

•          Pathogen resistance in food crops,

•          Toxin elimination in crops,

•          Advanced food processing for enhanced nutritional value,

•          Cutting-edge food analysis techniques,

•          Alternative food sources,

•          Valorization of food waste, and

•          Preclinical and clinical studies unveiling new health benefits of foods.

Dr. Netticadan expressed gratitude for the global response, saying, “We are blessed to achieve our mission of providing the latest knowledge to audiences worldwide, especially those with limited resources.” He humorously added, “Much work remains to engage Antarctica’s potential audience – penguins, seals, and winter birds!”

Acknowledging the event’s success, Dr. Netticadan praised the organizing team and funding organizations, including the St. Boniface Hospital Research Centre and AAFC, saying, “It was heartwarming to see the entire ‘village’ come together to make this enormous event possible.”

This landmark conference underscores the growing global interest in leveraging agri-food research to improve health outcomes and foster sustainable innovation.

As we reflect on this past year, we are filled with gratitude for our incredible friends, colleagues, and supporters. Together, we’ve made strides in advancing important heart, mind and gut-health research and improving the health and well-being of our community and beyond.

This holiday season, we celebrate the spirit of hope, discovery, and collaboration that fuels our work. Thank you for your unwavering support, which inspires us to continue our mission of innovation and excellence in research.

From all of us at the Albrechtsen Research Centre and Asper Clinical Research Institute, we wish you and your loved ones a joyful holiday season and a New Year filled with health, happiness, and continued success.

We look forward to achieving even greater strides towards better health, together in 2025!

Warm regards,
The St. Boniface Hospital Research Team

In a powerful editorial, Dr. Michael Czubryt, Executive Director of Research, St. Boniface Hospital, alongside fellow HealthCareCAN leaders David Hill and Ellen Chesney contributed to a bold new vision for Canadian health research, published online by the Canadian Science Policy Centre. This collaborative effort outlines key strategies to position Canada as a global leader in innovation, workforce development, and health outcomes.

At the 11th Annual Meeting of the International Academy of Cardiovascular Sciences (IACS) North American Section, held from September 19-21 at the Texas Heart Institute in Houston, TX, Principal Investigator Dr. Sanjiv Dhingra and three students from the Institute of Cardiac Sciences here at St. Boniface Hospital Research were recognized with awards.

The event featured notable speakers from ICS, including Dr. Michael Czubryt, Dr.Amir Ravandi, Dr. Sanjiv Dhingra, Dr. Lorrie Kirshenbaum, Dr. Grant Pierce, Dr. Naranjan Dhalla, and Dr. Inna Rabinovich-Nikitin, along with students Molly Crandall, Hannah Zhang, Keshav Alagarsamy, and Sikta Chattopadhyaya. This conference, previously hosted in Winnipeg in 2022 and Tampa in 2023, continues to draw top-tier cardiovascular researchers from across North America.

Dr. Dhingra was honored with the Jay Mehta Annual Award for Established Investigators, recognizing his remarkable contributions to the field.

A special congratulations to Sikta Chattopadhyaya, who won the Gary Lopaschuk Graduate Student Award, emerging victorious against three U.S.-based finalists, and Hannah Zhang and Keshav Alagarsamy, who each received the Morris Karmazyn Poster Award.

The IACS was founded in 1996 and is headquartered in Winnipeg with members from around the world. The North American Section is currently led by Dr. Michael Czubryt, while Dr. Grant Pierce serves as President of the global Academy. The organization also has sections in South America, Europe, and India. You can learn more about the Academy on its official website: https://iacsworld.com/

The second edition of Adult Stem Cells: Methods and Protocols, edited by Dr. Sanjiv Dhingra, Dr. Paolo di Nardo, and Dr. Vincenzo Desiderio, has drawn great interest since its release in early August.  Building on the success of the first edition, which has seen nearly 100,000 purchases worldwide, the second edition has already garnered over 7,400 downloads, signaling a strong response from the global scientific community.

This new volume offers an in-depth exploration of the rapidly growing field of stem cell therapies, with a focus on personalized medicine and tissue engineering. The chapters provide detailed protocols on advanced techniques, including stem cell isolation, characterization, and the generation of induced pluripotent stem cells (iPSCs). iPSCs, derived from a patient’s own genome, hold great promise for personalized treatments, especially for rare genetic disorders.

This edition also introduces readers to the intersection of nanotechnology and regenerative medicine. It covers topics such as nanoparticles, 3D scaffolds, and new biomaterials designed to enhance the survival of transplanted stem cells. These advancements address a key challenge in stem cell therapies—ensuring that transplanted cells remain viable in the body’s tissues.

Dhingra is particularly proud of how this book emphasizes protocols and process, versus theory. 

“Researchers and clinicians interested in advancing personalized drug therapy and regenerative medicine will find this volume an invaluable resource, as it provides crucial insights into translating cutting-edge stem cell technologies into practical clinical treatments,” he said.

Protocols for optimizing tissue regeneration, highlighting the collaboration between biomedical and engineering fields are also included. “By presenting novel techniques, the book emphasizes the shift from traditional medicine to personalized approaches, offering more effective treatments for degenerative diseases tailored to individual patients,” Dhingra added.

Special thanks are extended to Katie Bak for her contributions in collecting, revising, and proofreading the chapters. For more, visit Adult Stem Cells: Methods and Protocols, Second Edition, visit Springer

Dr. Sanjiv Dhingra, Principal Investigator at the Cardiac Regeneration and Tissue Engineering Program, Institute of Cardiovascular Sciences, has recently received significant funding from the Canadian Institutes of Health Research (CIHR). This includes $1.067 million over five years to tackle a major challenge in stem cell therapy for heart repair. His application was ranked 2nd within the committee.

“With heart disease remaining the leading cause of death worldwide, recent advancements in stem cell therapies offer new hope. However, there are still obstacles to overcome before these therapies can be widely used in patients,” said Dhingra, who is also Professor Regenerative Medicine Program, Department of Physiology and Pathophysiology, University of Manitoba.

Since 2013, Dhingra’s lab has been focused on finding ways to repair heart tissue damaged by heart attacks or other conditions using stem cells and specialized biomaterials. His current research centers on understanding how donor stem cells behave once transplanted into damaged heart tissue, which is crucial for making these treatments work in patients.

The project, titled “Role of Immunoproteasome in the Loss of Immunoprivilege of Mesenchymal Stem Cells in the Ischemic Heart,” aims to uncover why Mesenchymal stem cells (MSCs), which are typically immune-resistant, become vulnerable to immune attack in low-oxygen (ischemic) conditions. MSCs, derived from the bone marrow of young, healthy donors, have shown promise in repairing damaged hearts. These cells help suppress the immune response, which is vital for recovery after a heart attack. However, many patients’ immune systems reject these donor cells, reducing their effectiveness.

Dr. Dhingra’s research focuses on how hypoxia (lack of oxygen) affects MSC behavior, causing them to switch from immune-resistant to immune-reactive. The studies in this project will also focus on understanding how stem cells from male and female donors behave once transplanted into damaged heart tissue. By investigating the underlying mechanisms, the lab aims to develop strategies that improve the survival of transplanted stem cells, potentially enhancing patient outcomes and advancing heart repair treatments.

This innovative research has the potential to revolutionize stem cell therapy for heart disease, offering hope for improved recovery and a better quality of life for those affected.

Dr. Ruchira Nandasiri, a distinguished Postdoctoral Fellow with the Canadian Centre of Agri-Food Research in Health and Medicine (CCARM) here at St. Boniface Hospital Research, has recently achieved two remarkable milestones in his academic and professional journey.

Acceptance into the McCall MacBain Postdoctoral Fellows Teaching and Leadership Program

Nandasiri was selected as one of only 20 postdoctoral fellows from across Canada to join the prestigious McCall MacBain Postdoctoral Fellows Teaching and Leadership Program that began this September. Designed to cultivate the next generation of educators, researchers, and leaders by enhancing teaching skills, leadership capabilities, and interdisciplinary collaboration, the program will provide him with valuable training and experiences to further his development as a leading scholar and innovator in his field, under the supervision of Dr. Miyoung Suh, Professor Food and Human Nutritional Sciences, University of Manitoba.

Research Manitoba Research Connection Grant Award

In addition to his program acceptance, Nandasiri has been awarded the Research Manitoba Research Connection Grant. This $6,500 grant will support his travel to the OCN (Opaskwayak Cree Nation) for crucial research activities related to his project, “Empowering Communities: The Collaborative Journey to Health Equity.”

This funding will aid in advancing his innovative work on profiling bioactive compounds in smart farm vegetables and exploring their efficacy in combating type 2 diabetes. His research also aims to enhance nutritional offerings for First Nation communities through functional vegetable-fortified Indigenous foods.

His ongoing research and these new achievements reflect his commitment to advancing the field of agri-food health and medicine. His aspiration to pioneer precision agriculture-based nutrition highlights his dedication to addressing critical health issues and contributing to community well-being.

“We are delighted for Ruchira and know he will move onto greater and greater achievements as his career progresses,” said Dr. Miyoung Suh, Principal Investigator Nutrition and Neurological Diseases, CCARM, as well as a Principal Investigator with the Division of Neurodegenerative Disorders, Albrechtsen Research Centre.

The Youth BIOlab at the St. Boniface Hospital Albrechtsen Research Centre is thrilled to announce its success in the 2023 NSERC PromoScience grant competition. This award will provide $283,500 over three years to support the lab’s operating costs and enhance its outreach efforts to Indigenous youth in northern, rural, and remote schools in partnership with the Frontier School Division.

Today, Yasir Naqvi, Parliamentary Secretary to the Minister of Health, and Ryan Turnbull, Parliamentary Secretary to the Deputy Prime Minister and Minister of Finance and Parliamentary Secretary to the Minister of Innovation, Science, and Industry, on behalf of the Honourable François-Philippe Champagne, Minister of Innovation, Science, and Industry, announced funding for 44 science promotion and outreach programs, including the Youth BIOlab. The announcement took place at the University of Ottawa, highlighting over $10 million in investments through NSERC’s PromoScience program aimed at engaging and inspiring young Canadians in STEM.

The Youth BIOlab, established in 2013 with an initial investment of $450,000 from Manitoba Education, has engaged over 40,000 students through hands-on biomedical science learning experiences. These programs are designed to align with Manitoba curriculum outcomes, ensuring educational relevance and impact. The lab’s success is underpinned by partnerships with local school divisions and sustained funding from diverse sources, including yearly contributions from partner school divisions, federal grants, and donations.

With the new funding from NSERC, the Youth BIOlab will focus on its project, “Learning Together: Life Science for Youth and Teachers in Manitoba’s North.” This initiative will provide enhanced STEM education opportunities to underserved Indigenous youth, fostering a deeper understanding of science and health.

“We are incredibly honored to receive this funding from NSERC’s PromoScience program,” said Stephen Jones, Director of Youth BIOlab. “This grant will enable us to expand our outreach to northern and remote communities, providing vital STEM education to Indigenous youth. We are committed to inspiring the next generation of curious minds and helping them understand the science behind health.  NSERC has generously supported our work for more than a decade and this renewed funding will significantly enhance our efforts.”

This funding will support a variety of programs including visits to the Youth BIOlab, classroom workshops, and online learning programs, ensuring that youth in remote communities have the same access to innovative STEM education as their urban counterparts. Engaging youth in STEM is crucial for developing the problem-solving and critical thinking skills necessary for success in the 21st century.

The Youth BIOlab represents a joint commitment by the province and St. Boniface Hospital to the future of young people in Manitoba. By fostering interest in science and supporting participation in healthcare and research sectors, the BIOlab helps students gain a fundamental understanding of the science behind their own health.

In a world that is increasingly interconnected, celebrating diversity and fostering inclusion has become not just a goal, but a necessity. Recognizing this imperative, the Health Sciences Graduate Students’ Association (HSGSA) at St. Boniface Hospital Research (SBRC), led by Vice President Leena Regi Saleth, in collaboration with Shiqi Huang, the Canadian Centre for Agri-Food Research in Health and Medicine (CCARM) trainee representative, to promote multicultural understanding among staff and students.

The brainchild of Saleth and Huang, the Multicultural Event Series at SBRC aimed to create a platform for dialogue, appreciation, and celebration of different cultures within the SBRC community. With the help of enthusiastic student volunteers, this initiative brought to life the vibrant tapestry of cultures represented within SBRC through a series of six festivals held over the course of two semesters.

A Celebration of Cultures

The Multicultural Event Series kicked off with the Chinese Mid-Autumn Festival on Sept. 28, followed by the Indian festival of Diwali on Nov. 14, then the South Indian Harvest Festival of Pongal on Jan. 17.  March 20 brought the Persian New Year of Nowruz, followed by the Sri Lankan Sinhala and Tamil New Year on April 9, and concluded with the Islamic festival of Eid-al-Fitr on April 17. Each event showcased the unique traditions, cuisines, and customs associated with the respective cultures, providing attendees with an immersive experience.

“Participation in the various events that are organized by the students at St. Boniface Hospital campus is always valued,” shares Dr. Bram Ramjiawan, Director of Research and Director of Research Innovation and Regulatory Affairs. “It is an opportunity to expand our understanding of others, celebration and for growth. The work and kindness of the organizers are so appreciated.”

Building Bridges Through Culture

These events served as more than just cultural showcases; they were opportunities for community building and cross-cultural exchange. As Shiqi Huang reflects, “This event allowed me to not only introduce the Chinese culture to others in this family but also make friends with many folks working at other divisions/floors who I seldom have opportunities to meet usually especially during the pandemic.”

Embracing Diversity

For Leena Regi Saleth, the series was a personal journey of connection and sharing. “It was a blessing to prepare traditional dishes from my homeland, Tamil Nadu, and seeing everyone savor these authentic flavors and delve into the traditions of our harvest festival, a beautiful tradition that honors nature’s abundant resources for cultivation, was truly rewarding,” she shares.

Fostering Understanding

The Multicultural Event Series also provided an opportunity for individuals to learn about cultures different from their own, fostering greater understanding and appreciation. Danah Alhattab, who helped organize the Eid-al-Fitr celebration, remarks, “Hosting the Eid Al Fitr celebration not only allowed me to share my religious traditions but also fostered a sense of mutual respect, understanding, and compassion by encouraging cultural exchange and appreciation.”

Acknowledging Support

The success of the Multicultural Event Series would not have been possible without the support of various individuals and organizations. HSGSA and CCARM provided funding for the events, while volunteers from across SBRC dedicated their time and effort to make each celebration a memorable one. Special thanks to Dr. Michael Czubryt and Dr. Thomas Netticadan for their generous support, along with the invaluable assistance of Robert Blaich, Karen Swanson, Rhea Lopez, and Julie Schoffner.

Looking Ahead

As described by Executive Director, Dr. Michael Czubryt, diversity has been a hallmark of the Research Enterprise since its doors opened nearly 40 years ago. “Events like this reinforce our connections, and deepen our understanding of one another. I’m very proud of, and thankful for, our students’ efforts and initiative to establish this multicultural event series. I personally learned a lot, and appreciated the chance to share in the celebrations of our local-yet-global community,” he says.

As SBRC continues to champion diversity and inclusion, initiatives like the Multicultural Event Series serve as reminders of the richness that comes from embracing different cultures and perspectives. Through dialogue, collaboration, and celebration, SBRC is paving the way for a more inclusive future.

Special thanks to the volunteers for each festival: Hannah Zhang, Akshi Malik, Rohini Suresh and Danah Alhattab from ICS; Sadaf Asfa and Reza Arshinchi from DND; Soulmaz Naserli, Leila Tawakoli, Chamali Kodikara, Vinuri Weerasinghe, Shanella Senadhiraja, Dr. Champa Wijekoon, Dr. Ruchira Nandasiri, Ali Sabra and Fadi Ramadan, from CCARM.

For the 12th year in a row, the St. Boniface Hospital is among Canada’s leading research hospitals, taking the #1 spot in western Canada and ranking in the Top 5 nationally in the small hospital category, according to data released by Research Infosource Inc. Canada’s source of R&D intelligence.

“We have a great team of researchers, engaged in studies from the lab bench to the bedside, and covering science, medicine, health and wellness from a wide variety of perspectives. The support received from our partners, including the St. Boniface Hospital Foundation and the people of our community, makes this work possible. We are pleased and proud to see this recognition of the impactful work carried out at St. Boniface Hospital Research,” says Dr. Mike Czubryt, Executive Director of Research, St. Boniface Hospital.

St. Boniface Hospital has always recognized the power of the research discoveries and potential interventions the talented cardiac, brain, food sciences and clinical research teams are pursuing.  

“It’s great to see our strength in research recognized nationally and celebrate the leading position we have held for a dozen years now, says Nicole Aminot, President & CEO, St. Boniface Hospital. “This is a very proud day for Dr. Czubryt and his colleagues and team at the Albrechtsen Research Centre and Asper Clinical Research Institute – congratulations!”

In affiliation with the University of Manitoba, the University of Winnipeg and Agriculture & Agri-Food Canada, St. Boniface Hospital Research has four dedicated research programs: the Institute of Cardiovascular Sciences; the Division of Neurodegenerative Disorders; the Canadian Centre for Agri-Food Research in Health and Medicine (CCARM); and Clinical Research.  It boasts 30 laboratories, 200 staff, served as training ground for more than 450 students and is also home to the RBC Youth BIOLab Jeunesse —a space for students and teachers to explore and experience real biomedical science in a world-class research center.

About Research Infosource Inc.
Research Infosource Inc., a division of The Impact Group, publishes Canada’s Innovation Leaders, which includes Canada’s Top 100 Corporate R&D Spenders List, Canada’s Top 50 Research Universities List, Canada’s Top 40 Research Hospitals List and Canada’s Top 50 Research Colleges List.

With help from the ‘pros’, the Minister of Education and other special guests were treated to science demos, birthday cake, and lots of fun at a very special celebration at the Youth BIOlab last Thursday. Celebrating 10 years of on-site health literacy and science programming to students from across the province, YBL friends and ‘family’ turned out for an afternoon filled with smiles and learning. Many thanks to: The Honourable Nello Altomare, Minister of Education and Early Childhood Learning; Christian Michalik, Superintendent and CEO, Louis Riel School Division; Nicole Aminot, President and CEO, St. Boniface Hospital; Lisa Thomson Stifora, Director of Communications and Stewardship, St. Boniface Hospital Foundation; and Dr. Michael Czubryt, Executive Director, Research, St. Boniface Hospital, for sharing in this day and showing your support.

Exciting day at St. Boniface Hospital Research. Mayor Scott Gillingham visited the Albrechsten Research Centre, where groundbreaking discoveries are shaping the future of healthcare. Thank you, @ScottGillingham for recognizing the vital work happening right here in our community! @STBHF @sbhwpg

If handling pigs’ hearts and sheep’s brains grossed them out, the smiles on their faces did not let it show.

Four students from the remote community of Brochet in Northern Manitoba were introduced to authentic, hands-on science experiences in Winnipeg this month. This was thanks to a generous in-kind donation from Winnipeg’s Exchange Income Corporation (EIC).

The Brochet youth and their two chaperones joined dozens of others from the Frontier School Division on a field trip to the RBC Youth BIOlab Jeunesse at the St. Boniface Hospital Albrechtsen Research Centre.

For many of them in Grades 2 to 8, it was their first time being in a real science lab.

Facilitators Meghan Kynoch, Program Coordinator, and Anjelica Bodnaryk, Education Liaison, guided students in the packed lab. The kids looked at both mouse heart cells and cells swabbed from their own cheeks under microscopes. They also handled and examined animal hearts and preserved brains.

Perimeter Aviation provided flights

Exchange Income Corporation subsidiary Perimeter Aviation flew the group from Brochet School to Winnipeg. EIC is focused on aerospace and aviation services and equipment, and manufacturing.

“The areas we serve are remote northern communities.. As an organization we believe in supporting and fostering growth,” said Charity Scantlebury, Director of Marketing and Communications at Perimeter Aviation.

The trip to Winnipeg was a way for the kids from Brochet to see and try things they might not have access to otherwise. “School introduces students to opportunities they can pursue, but I think the Youth BIOlab is a place where kids can fall in love with science,” she said.

Stepping outside the noisy Youth BIOlab for a quick chat, Scantlebury explained that Perimeter promotes and supports three pillars: “Mental health, education and training, and healthy and active living. In terms of delivering on our pillars, the Youth BIOlab is a great fit,” said Scantlebury.

Frontier School Division spans nearly 75 per cent of the province and is organized into five Areas. Coming from about 15 different northern and remote communities across the Division, the students attended Youth BIOlab sessions from March 14 to 16. They also participated in their annual Science Fair held at the new Royal Aviation Museum of Western Canada.

“The kids love the Youth BIOlab. They love it! They are exhausted by the end of the day, seeing hearts and brains and all kinds of fun things,” exclaimed Arif Kassum, a Science Instructional Coach with Frontier School Division and facilitator of the Science Fair.

“We are trying to show them that there is a lot more to science than just textbooks and little classroom experiments. There are these kinds of opportunities,” said Kassum.

“They have such a great scope and range of activities available here, depending on the grade level. And they get into everything important, especially when it comes to biomedical research,” he said.

The support from EIC is important, Kassum added. “Our schools have limited budgets that don’t allow students to travel long distances, let alone fly, because of the costs. So, having any type of outside funding and support provides students the opportunity to come to Winnipeg, which they would not have.”

Funds the Youth BIOlab program received in August 2020 from the Manitoba Métis Heritage Fund and matched by the Manitoba Métis Federation helped cover the costs of ground transportation for many of the other Frontier School Division groups on the trip.

“Steve (Jones, Youth BIOlab Director), Meghan, and Anjelica do an incredible job of keeping our students going and interested in science. They are keeping it relevant because a lot of the things the kids are learning are directly related to Manitoba’s science curriculum,” said Kassum.

Since opening in 2013, the Youth BIOlab has welcomed more than 75,000 students like the ones from Brochet School and exposed them to careers and ideas in medicine and research.

Not all of them are destined to become doctors and researchers, of course. With that in mind, the Youth BIOlab facilitators designed programming to teach all kids who visit about health literacy. By connecting them with the science of health in a meaningful way, the Youth BIOlab helps kids understand their own health, and helps them connect their classroom learning to cutting-edge science.

_{Thanks to St. Boniface Hospital Foundation for sharing this story.}

For the 11th year in a row, the St. Boniface Hospital is among Canada’s leading research hospitals, taking the #1 spot in western Canada and ranking in the Top 5 nationally, according to data released today by Research Infosource Inc. Canada’s source of R&D intelligence.

“We have a phenomenal team of researchers, clinicians and students at St. Boniface Hospital Research, and it is wonderful to see their efforts recognized. The outstanding partnership we enjoy with the University of Manitoba, the University of Winnipeg, and Agriculture & Agri-Food Canada, along with the support of donors through the St. Boniface Hospital Foundation, is critical for generating new discoveries that broaden our understanding of disease and its treatment,” says Dr. Mike Czubryt, Executive Director of Research, St. Boniface Hospital.

St. Boniface Hospital has always recognized the power of the research discoveries and potential interventions the talented cardiac, brain, food sciences and clinical research teams are pursuing.

“Congratulations to our science leaders at the Albrechtsen Centre and Asper Clinical Research Institute,” says Nicole Aminot, President & CEO, St. Boniface Hospital, “We are tremendously proud to be home to some of the most internationally recognized experts in the fields of cardiovascular, neurodegenerative and food science research.”

In affiliation with the University of Manitoba, the University of Winnipeg and Agriculture & Agri-Food Canada, St. Boniface Hospital Research has four dedicated research programs: the Institute of Cardiovascular Sciences; the Division of Neurodegenerative Disorders; the Canadian Centre for Agri-Food Research in Health and Medicine (CCARM); and Clinical Research.  It boasts 30 laboratories, 250 staff, served as training ground for more than 450 students and is also home to the RBC Youth BIOLab Jeunesse —a space for students and teachers to explore and experience real biomedical science in a world-class research center.

Hospital Research Spending Flatlines
Toronto ON, 31 January 2023. Canada’s Top 40 Research Hospitals, Hospital Networks and Health Authorities reported a combined $3.06 billion to research in Fiscal 2021, indicating flat 0.1% growth over Fiscal 2020, according to Research Infosource Inc., which today released its annual Top 40 Research Hospitals ranking. Over half (23) of the organizations lowered their research spending in Fiscal 2021, while 17 others increased research spending. The number of researchers nationwide increased by 3.9% to 9,889. For more on this, visit: RE$EARCH Infosource Inc. (researchinfosource.com)

About Research Infosource Inc.
Research Infosource Inc., a division of The Impact Group, publishes Canada’s Innovation Leaders, which includes Canada’s Top 100 Corporate R&D Spenders List, Canada’s Top 50 Research Universities List, Canada’s Top 40 Research Hospitals List and Canada’s Top 50 Research Colleges List.